Northern Vertex Announces PEA for the Moss Mine Gold-Silver Project

?Northern Vertex Mining Corp. (TSXV:NEE) released the results of a preliminary economic assessment for its Moss Mine Gold-Silver Project in Mohave County Arizona, USA: Pre-Tax IRR 117.9%, NPV @5% $110 Million USD, Payback Period 1.25 Years.

As quoted in the press release:

Highlights are as follows:

Mine life 5 yrs, 5000 tpd, 42,000 AuEq oz/yr
Pre-tax IRR of 117.9%
Pre-tax payback of 15 months
Pre-tax NPV @5% $110 million
Capital expenditures $26.6 million
Capital / average annual oz AuEq production $633/oz
Cash Costs/oz AuEq $490/oz

Click here to read the Northern Vertex Mining Corp. (TSXV:NEE) press release

Click here to see the Northern Vertex Mining Corp. (TSXV:NEE) profile.

Source: http://goldinvestingnews.com/33503/northern-vertex-announces-pea-for-the-moss-mine-gold-silver-project.html

Geminid meteor shower right to work Clackamas Town Center 12 12 12 Anne Hathaway Wardrobe Malfunction man of steel man of steel

Samsung's new Galaxy S 4 costs $50 more than iPhone 5

Suzanne Choney , NBC News ? ? ? 3 hrs.

AT&T said it will start pre-orders for the Samsung Galaxy S 4 and will charge $250, making the hot Android phone $50 more than Apple's entry-level iPhone 5, its biggest competitor.

The new phone is expected to be offered by all carriers, but AT&T is the first to announce pre-orders for the phone, beginning April 16.

The iPhone 5 with 16 GB is $199.99 with a two-year contract; the Samsung Galaxy S 4 with 16 GB will be $249.99 with a two-year contract.

Generally, phones that compete directly with the iPhone cost the same or less, because Apple products are perceived to carry the "Apple tax" ? a slightly inflated price tag ? due to the brand itself. AT&T is still selling Samsung's previous flagship, the Galaxy S III, for its original starting price of $199. An AT&T spokeswoman told NBC News Thursday the company had nothing to add when asked about the pricing of the S 4.

AT&T did not say on its consumer blog when the S 4 will be delivered to customers, but the phone is expected to be widely available by late April.

Here's what NBC News' Rosa Golijan had to say about the phone after a recent hands-on with it.

Check out Technology, GadgetBox, TODAY Tech and In-Game on Facebook, and on Twitter, follow Suzanne Choney.

Source: http://feeds.nbcnews.com/c/35002/f/653377/s/2a1b1f24/l/0L0Snbcnews0N0Ctechnology0Cgadgetbox0Csamsungs0Enew0Egalaxy0Es0E40Ecosts0E50A0Emore0Eiphone0E50E1C9124680A/story01.htm

ira glass swain match day nene dark shadows trailer nate mcmillan clooney arrested

Will Alabama Finally Let Its Citizens Brew Their Own Beer?

All around the country, homebrewers can proudly brag about their newest IPAs or chocolate porters. They can openly discuss their malts, their mash, and their wort. They can even pop into a local shop to pickup a bottling bucket or hydrometer. All around the country, that is, except in Alabama. But that may soon change.

Alabama is the last state in the country in which homebrewing is illegal. In fact, it?s illegal just to own the equipment to brew beer there. It?s a law that dates back to the end of prohibition, when states were given the right to issue their own laws governing the consumption and distribution of alcohol. But two bills?one in the state House of Representatives and the other in the state Senate? making it legal for individuals to make as much as 15 gallons of beer, wine, or hard cider every three months could pass as early as next week.

?Alabama is last again,? said Republican Bill Holtzclaw, the sponsor of the senate bill. ?When you try and think about reasons why the state doesn?t allow it, you just can?t come up with good answers.?

The popularity of craft beer and homebrewing has certainly been on the rise around the country. Just this past week, Mississippi became the 49th?state to legalize homebrewing, joining former holdout states like Utah and Oklahoma, which came on board within the last five years. Homebrewing became legal under federal law in 1978, and today The American Homebrewer?s Association estimates that there are now nearly one million people brewing beer or making wine in their homes at least once a year. Even the White House produced a Honey Ale last year.

But just because Bill?Holtzclaw?can?t think of points of opposition, that?doesn?t mean no one else can. Advocates who've been fighting for legalization since 2009 have been met?with sharp resistance from a religious group called the Alabama Citizen Action Program. Currently led by a Baptist pastor named Joe Godfrey, ALCAP has been fighting for temperance since it was founded in 1937.

Godfrey says there are a lot of issues at play here: children getting access to alcohol (?How will parents know if they take a swig from a gallon jug??); the policing of activities (?Nobody?s going to raid houses to make sure they aren?t making too much of it or selling it?); and the slippery slope argument (?Pretty soon you?re going to have a distiller say if you can make beer and wine, why not have a moonshine operation??).

Between ALCAP's opposition and the task of trying to pass alcohol legislation in a state with 26 counties that are at least partially dry, it?s been an uphill slog for homebrewers. In 2011, a House version of the bill failed so miserably it won the award for? ?deadest bill of the year.? There is an actual award for this. It comes in the shape of a coffin.

State Rep. Richard Laird told National Journal that he would not be supporting the bill this year because he is afraid that without enough oversight, underground connections between homebrewers and moonshiners could arise.

?If people start making and stockpiling beer, who?s to say the moonshiners wouldn?t come up and buy their supply and resell it,? he said.

Gary Glass, the Director of the American Homebrewers Association which has helped out on the bill, says it?s been the most difficult attempt at legalization he?s dealt with, including getting a bill through a mostly Mormon legislature in Utah. But this year, he believes the efforts will pay off.

?There used to be a perception that homebrewing and moonshining were the same thing,? Glass said. ?The perception has changed in the past years.?

While Laird, who is an independent in the state legislature, might not agree, it sounds as if Glass is right. Even Godfrey at ALCAP says he expects the bill to pass (?But not without me making them work for it?), and the governor has said he will sign it into law if it gets to his desk.

All this is music to Glass?s ears.

?Homebrewers should be able to operate in the open,? he said. ?And it?s not just about the hobby. This country has a unique beer culture, and many of these craft beers and new beer styles all start with someone making it in their home.?

Source: http://news.yahoo.com/alabama-finally-let-citizens-brew-own-beer-152217627--politics.html

whitney houston national anthem beverly hills hotel beverly hills hotel the watchmen whitney houston dies dolly parton i will always love you beverly hilton hotel

Rush Limbaugh: Regardless of Supreme Court Ruling Gay Marriage Is 'Inevitable'

Limbaugh

In his radio show today, conservative talk show host Rush Limbaugh said defenders of traditional marriage have lost the battle, even though the Supreme Court won't hand down its decisions for another few months.

"I don't care what the Supreme Court does, this is now inevitable," Limbaugh said, "and it's inevitable because we lost the language on this."

Limbaugh took issue with the idea that the word marriage was already applied to gay couples. Therefore, he asserted, modifiers like "hetero" or "opposite-sex" are now at times added to denote a union between a man and a woman.

"I maintain to you that we lost the issue when we started allowing the word 'marriage' to be bastardized and redefined by simply adding words to it - because marriage is one thing, and it was not established on the basis of discrimination. It wasn't established on the basis of denying people anything," the radio host said. "Marriage is not a tradition that a bunch of people concocted to be mean to other people with. But we allowed the left to have people believe that it was structured that way."

On Wednesday, he made a similar prediction, saying that gay marriage would soon become legal " nationwide."

Earlier this year, Limbaugh compared homosexuality to pedophilia.

Today, he claimed discrimination against gay couples "is not an issue."

"No one sensible is against giving homosexuals the rights of contract or inheritance or hospital visits. There's nobody that wants to deny them that. The issue has always been denying them a status that they can't have, by definition. By definition - solely, by definition - same-sex people cannot be married. So instead of maintaining that and holding fast to that, we allowed the argument to be made that the definition needed to change, on the basis that we're dealing with something discriminatory, bigoted, and all of these mystical things that it's not and never has been."

Also Read

Source: http://news.yahoo.com/rush-limbaugh-regardless-supreme-court-ruling-gay-marriage-234407342--abc-news-politics.html

Hurricane Isaac 2012 Snooki Baby terrell owens terrell owens neil armstrong little league world series us open tennis

CBS renews 18 prime-time series for next season

NEW YORK (AP) ? There's little suspense ahead for CBS viewers: The nation's most popular broadcaster said Wednesday that it has renewed 18 of its prime-time series for next season.

The long-running comedy "Two and a Half Men" was not on the list, but CBS said it's discussing another season with the show's production company, Warner Bros. Television.

CBS has been dominant in the ratings this year and lately has taken to predating the annual release of its fall schedule in May with an announcement of mass renewals earlier in the spring. The renewals include news shows "60 Minutes" and "48 Hours" and reality shows "Survivor," ''The Amazing Race" and "Undercover Boss."

Dramas back on the schedule next fall are the top-rated "NCIS" and its spinoff, "NCIS: Los Angeles." Other returning shows are "Elementary," ''CSI: Crime Scene Investigation," ''Person of Interest," ''Hawaii Five-0," ''The Mentalist," ''Blue Bloods" and "The Good Wife." Renewed comedies are "The Big Bang Theory," ''How I Met Your Mother," ''2 Broke Girls" and "Mike & Molly."

"How I Met Your Mother" will have its final season and, presumably, answer the mystery of who the mother actually is.

The shows still on the bubble are "CSI: NY," ''Vegas," ''Golden Boy" and "Rules of Engagement." CBS may renew some or none of those shows, depending on its development of new programs.

Source: http://news.yahoo.com/cbs-renews-18-prime-time-series-next-season-203850791.html

bobby abreu 2012 draft colt mccoy arbor day mike adams janoris jenkins john edwards trial

Flipboard 2.0 lets create your own magazines

The popular news app Flipboard has been updated to 2.0 and introduces the ability to make your own magazines. These magazines are made of content you find and collect on Flipboard or the web (with a bookmarklet). The magazines are public and your friends can like and comment on stories.

Tapping the [+] will "flip" the item you?re looking at into your very own Flipboard magazine. Magazines are great for collecting the things you discover and they can be shared publicly or kept private just for you. For example, you can create a beautiful magazine full of all the places you want to explore or all the books you want to read.

When you create a magazine, you can share it to your favorite social networks to ask your friends to subscribe. Unfortunately, magazines can only be viewed with the Flipboard app, so if a friend clicks your link from a computer, they will not be able to see the content of your magazine -- just an invitation to get the app.

The new magazine feature reminds me a lot of Pinterest. Instead of boards, you have magazines, but it's essentially the same idea.

What do you think of Flipboard 2.0? Have you created any magazines, yet? If so, what topics do they cover? Feel free to share them in the comments below!

• Free - Download now

Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/XwrrmTmvJGo/story01.htm

Russell Means Taylor Swift Red Walking Dead Season 3 Episode 2 celiac disease san francisco giants Medal of Honor Warfighter Richard Mourdock

Chillingo goes all-in with Android - Endless Road, He-Man, and more on the way

One of my favorite mobile game publishers, Chillingo, was at GDC 2013 and we got to catch up with them and hear about all of the awesome titles that are coming to Android. Some are already out, like Parking Mania and Contre Jour, but others like He-Man, Puzzle Craft, and Endless Road are on the way, and others still like Catapult King just came out. We only got to try out a few of these, but Chillingo's catalog is really impressive, and it will be great to see more of their stuff hitting Google Play this year. 

What are your favorite Chillingo games? Any other publisher that you have a particular fondness for? 

Source: http://feedproxy.google.com/~r/androidcentral/~3/1m8GBb5lg1A/story01.htm

ipad 2 wal mart happy thanksgiving Macys Thanksgiving Day Parade 2012 Turkey Cooking Times Butterball mashed potatoes

Singer Dionne Warwick files for bankruptcy in NJ

NEWARK, N.J. (AP) ? Singer Dionne Warwick claims in a recent bankruptcy filing that she owes nearly $10 million in back taxes and her monthly expenses exceed $20,000.

The South Orange resident and singer of classics such as "Walk On By," ''I Say a Little Prayer" and "Do You Know the Way to San Jose" filed a Chapter 7 petition in U.S. bankruptcy court in New Jersey last Thursday.

In the filing, the 72-year-old Warwick listed liabilities that include nearly $7 million owed to the Internal Revenue Service for the years 1991 to 1999 and more than $3 million in business taxes owed to the state of California.

Warwick, a cousin of the late Whitney Houston, also listed $20,950 in monthly income from royalties, retirement income and a contract with Culver City, Calif.-based Star Girl Productions. Her monthly expenses total $20,940 and include $5,000 for housekeeping/housesitting.

Warwick's publicist said that the singer was victimized by bad financial management in the 1990s and that she has paid back the actual amount of the taxes, but penalties and interest have accumulated over the years.

"In light of the magnitude of her tax liabilities, (Dionne) Warwick has repeatedly attempted to offer re-payment plans and proposals to the IRS and the California Franchise Tax Board for taxes owed," Kevin Sasaki said in an email Tuesday. "These plans were not accepted, resulting in escalating interest and penalties. Although the actual amount of back taxes owed has been paid, the resulting penalties and interest has continually accrued."

Source: http://news.yahoo.com/singer-dionne-warwick-files-bankruptcy-nj-210030788.html

love actually strikeforce davy jones deep impact miesha tate vs ronda rousey idiocracy usssa baseball

Brightstar revealed as mystery company that bought 1 million BlackBerry 10 devices

In his new cover story for New York magazine, Joe Hagan offers the most in-depth look at the Today?show ratings?disaster that has created Matt Lauer's weeks-long attempt at image rehabilitation, and it's now clear that the defining moment that brought the morning show crashing own to Earth ? the exit of Ann Curry ? was something of a cross between the fourth circle of Hell and?and running with the Heathers?in high school: Curry got pranked, she got her clothes made fun of, she was prevented from reaching out to Robin Roberts, and her legacy lives on as a ...

Source: http://news.yahoo.com/brightstar-revealed-mystery-company-bought-1-million-blackberry-201700642.html

geithner gabrielle giffords juliette lewis chelsea handler mitch daniels shirataki noodles prince fielder

Syrian opposition takes Syria's Arab summit seat

DAMASCUS, Syria (AP) ? Syria's opposition took over the country's seat for the first time at an Arab summit Tuesday in a diplomatic triumph marred by severe divisions in the ranks of the Western-backed opposition alliance.

The opposition's ascension to representing the country at the summit in Qatar, a key backer of the those fighting to topple President Bashar Assad, demonstrated the extent of the regime's isolation two years into a ferocious civil war that the U.N. says has killed an estimated 70,000 people.

In Damascus, the government on Tuesday blasted the Arab League's decision, portraying it as a selling-out of Arab identity to please Israel and the United States.

"The shameful decisions it (Arab League) has taken against the Syrian people since the beginning of the crisis and until now have sustained our conviction that it has exchanged its Arab identity with a Zionist-American one," said an editorial in the Al-Thawra newspaper, a government mouthpiece.

The Qatari ruler, who chaired the summit, said the Syrian opposition deserves "this representation because of the popular legitimacy they have won at home and the broad support they won abroad and the historic role they have assumed in leading the revolution and preparing for building the new Syria."

In a further show of solidarity with anti-Assad forces, the Arab League endorsed the "right of each state" to provide the Syrian people and the Free Syrian Army with "all necessary means to ... defend themselves, including military means."

It was unclear whether the statement would open new weapons channels to fighters. But it would mark a symbolic slap of the U.S. and European allies that have resisted full-scale military aid to the rebels.

Arab League Secretary-General Nabil Elaraby told reporters that the call for "rights" to aid rebels is not an end to diplomatic efforts to solve Syria's crisis, but seeks to provide more "balance" with Assad's superior firepower and aid he is getting from Russia and Iran.

"The right to send more weapons to support the opposition is not an end to political efforts, but this might establish balance between both parties," Elaraby said.

Fighting, meanwhile, raged on in Syria. Rebels barraged Damascus with mortar shells that killed at least three people and wounded dozens in one of the most intensive attacks on the seat of President Bashar Assad's power.

The state news agency also reported that a car bomb exploded near the predominantly Kurdish neighborhood of Rukneddine, killing three people.

The opposition delegation led by Mouaz al-Khatib, the former president of the main opposition alliance ? the Western-backed Syrian National Coalition ? took the seats assigned for Syria at the invitation of Qatar's emir, Sheik Hamad bin Khalifa Al Thani, while other delegates applauded.

Al-Khatib used the forum to call for a greater U.S. role in aiding the rebels and said he had appealed to Secretary of State John Kerry to consider using NATO Patriot anti-missile batteries in Turkey to help defend northern Syria against strikes by Assad's forces.

Asked about al-Khatib's request for Patriots, State Department spokesman Patrick Ventrell said the deployment of the anti-missile batteries to Turkey was a NATO decision with a clear mandate to protect Turkey.

"We've heard some of this before in private," Ventrell told reporters in Washington. "He's now publicly saying this. But again, that's what the NATO mission is."

A NATO official said "the secretary general of NATO has been very clear since the beginning that NATO has no intention of getting militarily involved with Syria. That remains the same."

"Our current deployment of Patriot systems is a defensive action to protect our ally Turkey," said the NATO official in Belgium on condition of anonymity in keeping with the alliance's regulations.

The diplomatic triumph, however, could not conceal the disarray within the top ranks of the opposition and underlined the splits that continue to plague the opposition, complicating U.S. and Western efforts to try to shape the course of the fight to oust Assad.

Besides al-Khatib, the Syrian delegation included Ghassan Hitto, recently elected prime minister of a planned interim government to administer rebel-held areas in Syria, and two prominent opposition figures, George Sabra and Suheir Atassi.

Al-Khatib announced his resignation on Sunday because of what he described as restrictions on his work and frustration with the level of international aid for the opposition. The coalition rejected the resignation and al-Khatib said he would discuss the issue later and represent the opposition at the Qatar summit "in the name of the Syrian people."

Also, Hitto's election as the head of the interim government was rejected by the opposition's military office, which said he was not a consensus figure. Some members have accused Qatar and the Muslim Brotherhood of imposing their will on the Coalition.

Atassi briefly suspended her membership in the coalition after Hitto was elected.

Addressing the gathering, al-Khatib thanked the Arab League for granting the seat to the opposition and lamented the inaction of several foreign governments, which he did not name, toward the Syrian crisis despite the suffering of civilians in his country.

"I convey to you the greetings of the orphans, widows, the wounded, the detained and the homeless," al-Khatib told the gathering in an opulent hall in Doha.

Most of the mortar strikes hit the capital's east side, falling near a school in the Baramkeh neighborhood, the Damascus Hospital, the Law Faculty of Damascus University and the state news agency's own offices.

SANA said one girl and two other civilians were killed.

A government official in Damascus told The Associated Press that four people were killed and 42 wounded. The official spoke on condition of anonymity because he was not authorized to brief the media, and the discrepancy could not immediately be resolved.

Mortar rounds also fell in a number of areas on the city's west side, including the Christian neighborhood of Bab Touma, SANA said.

The agency published photos of a hole in a wall of what appeared to be a school, medics treating blood-stained patients and firemen extinguishing burning cars.

It was not immediately known who fired the mortar shells. Such attacks in the capital have grown more common in recent weeks as rebels have clashed with government troops on the city's east and south sides. While the shelling rarely causes many casualties, it has shattered the aura of normalcy the regime has tried to cultivate in Damascus.

"They think that that through this tactic they can pressure residents to rise up against authorities," said Fayez Sayegh, a member of parliament and a member of the ruling Baath Party. "But on the contrary, this indiscriminate shelling makes people realize that this opposition is nothing but gangs of criminal terrorists."

Meanwhile, anti-regime activists said Syrian troops seized control of a neighborhood in the central city of Homs that is considered a symbol of opposition to Assad's regime.

The Syrian military's recapture of Baba Amr, in Homs, while not strategically important in the civil war, is a symbolic blow to the rebels. The poor, predominantly Sunni neighborhood emerged early in the uprising as a symbol of the rebel movement, first for its protests and later for the armed groups who held it against the regime onslaught.

The seesaw fight for the Homs neighborhood reflects the back-and-forth nature of Syria's civil war. While rebels appear to be gaining ground, their progress is slow and their fighters remain vulnerable to Assad's military superiority.

In other violence Tuesday, the Observatory said that at least 13 charred bodies, including four children and five women, were found on the outskirts of the village of Abil, southwest of Homs city. It said local activists blamed the killings on pro-government gunmen.

The Syrian government does not respond to requests for comment and did not mention the killing in official media.

___

Mroue reported from Beirut. Associated Press writers Brian Murphy in Doha, Ben Hubbard in Beirut, Bradley Klapper in Washington, Tom Wagner in London, and Hamza Hendawi in Cairo contributed to this report.

Source: http://news.yahoo.com/syrian-opposition-takes-syrias-arab-summit-seat-192735251.html

luke scott tom benson royals nicole richie lyme disease symptoms esperanza spalding jessica sanchez

China Fund Chief Warns Japan on Yen

Article Excerpt

BY LINGLING WEI

BEIJING?The president of China's giant sovereign-wealth fund warned Japan against using its neighbors as a "garbage bin" by deliberately devaluing the yen, joining growing international griping about a potential currency war.

In unusually strong language, Gao Xiqing, president of China Investment Corp., echoed alarms from Latin America to Europe that the new Japanese government is aiming to boost its exports at other countries' expense via a weaker currency?allegations often leveled at China itself by the U.S. and others.

Mr. Gao's comments in an interview with The Wall Street Journal, among the strongest remarks yet by a senior Chinese official, signaled ...

Continue reading article with pop up player

Source: http://online.wsj.com/article/SB10001424127887324034804578343913944378132.html?mod=rss_asia_whats_news

Breaking Amish Indianapolis explosion jay cutler applebees jeff gordon veterans day mike brown

Kanye West Slams MTV Over Low "Hottest MCs" Ranking, Sort of Blames Kim Kardashian

Source: http://www.thehollywoodgossip.com/2013/03/kanye-west-slams-mtv-over-low-hottest-mcs-ranking-sort-of-blames/

aubrey huff the killers julianne hough brandy michael pineda charles taylor bruins

Healthy Expressions 2: Evolve Chiropractic Wellness Studio | Dishing

Located in Burlington at 378 PLAINS ROAD E | BURLINGTON, ONTARIO |? L7T 0A4 905-631-3000;? Evolve Chiropractic has been offering patients the tools to empower the patient to heal themselves through quality care, education and a positive experience.?

---

.

Dr. Laura?s interest in fitness and health lead her to pursue a degree in Kinesiology at the University of Waterloo. As a co-op student she was fortunate to have had the opportunity to be exposed to a variety of health related fields.? She quickly decided that natural health was going to be my focus.

Her belief is that if given the opportunity, the body will heal itself. and that natural alternatives to health issues should always be considered first.? Chiropractic seemed to make sense.? Dr. Lardi has had experience as a fitness supervisor and personal trainer and incorporates improving fitness levels into her practice.? Her approach is holistic ? Proper nutrition, exercise and living a healthy lifestyle ? help the patient to evolve toward optimal health and well-being.? She received training from points around the work in medical acupuncture and Active Release Techniques?, as well as treating musculoskeletal disorders related to the spine, nervous system and joints. She became a member of the International Chiropractic Paediatric Association and completed advanced training in chiropractic care for children and expectant mothers. Her training didn?t end there, a mother provides feedback regarding her toddler who was suffering from chronic ear infections and was able to avoid surgery once he began chiropractic care. She share the story below.
While chiropractic care is very effective for back pain, neck pain, headaches, and sports injuries, it is so much more than that!

Yours in Health,

Dr. Laura Lardi, B.Sc., D.C.

?We are very grateful and would strongly recommend chiropractic care to any parent whose child is suffering from acute or chronic ear infections?

My son Nicholas suffered from chronic ear infections for six consecutive months. They began when he started daycare at age 1. Every month his family doctor prescribed him Amoxicillin. He also saw an ENT who recommended Nicholas get tubes put into his ears. He ordered a hearing test and the results showed that his hearing was low due to fluid from the ear infections that was trapped in his ears. We were placed on a waiting list for surgery.
In May 2011, Nicholas was 18 months old and I had no idea how to help him other than surgery. No mother wants to see their child undergo surgery unless it?s absolutely necessary. A co-worker recommended chiropractic care as an alternative as she knew a chiropractor that treated children. My husband and I were hesitant initially as we did not know much about chiropractic care.
I decided to take Nicholas to see Dr. Lardi for a consultation. Upon examination, she knew she could help him. She informed me on what the treatment process would be. He would receive gentle chiropractic adjustments three times a week initially and then gradually decrease. She also showed me some simple things that I could do at home that would help in the healing process. It was very easy. Dr. Lardi also offered nutritional advice and recommended some specific changes be made to his diet. This was definitely an adjustment but very simple to do. Nicholas was also placed on a probiotic to boost his immune system which was weakened by his constant antibiotic use.
After discussing our options with my husband, we decided to pursue chiropractic care as an alternative to surgery as it was safe and less invasive than surgery.
Nicholas? results were immediately successful. He has had no ear infections since May 2011 when we began our first treatment. I took him back to see his ENT and he said Nicholas? ears had no fluid. We cancelled his surgery. We are very grateful and would strongly recommend chiropractic care to any parent whose child is suffering from acute or chronic ear infections.
Sincerely,

Like this:

Like Loading...

Source: http://gocooking.wordpress.com/2013/03/06/healthy-expressions-2-evolve-chiropractic-wellness-studio/

erin andrews tour de france Magic Mike Anderson Cooper Gay NBA draft 2012 alicia sacramone Don Grady

Seniors who play video games report better sense of emotional well-being

Mar. 5, 2013 ? New research from North Carolina State University finds that older adults who play video games report higher levels of emotional well-being.

Researchers asked 140 people aged 63 and older how often they played video games, if at all. The study participants then took a battery of tests to assess their emotional and social well-being. 61 percent of study participants played video games at least occasionally, with 35 percent of participants saying they played at least once per week.

The study found that participants who played video games, including those who only played occasionally, reported higher levels of well-being. Those who did not play video games reported more negative emotions and a tendency toward higher levels of depression.

"The research published here suggests that there a link between gaming and better well-being and emotional functioning," says Dr. Jason Allaire, lead author of a paper describing the study and an associate professor of psychology at NC State. "We are currently planning studies to determine whether playing digital games actually improves mental health in older adults. "

The paper, "Successful aging through digital games: Socioemotional differences between older adult gamers and non-gamers," was published online this week in Computers in Human Behavior. The paper was co-authored by Dr. Anne McLaughlin, an assistant professor of psychology at NC State; NC State Ph.D. students Amanda Trujillo, Laura Whitlock and Landon LaPorte; and Dr. Maribeth Gandy of the Georgia Institute of Technology. The research was supported by the National Science Foundation.

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:

---

Story Source:

The above story is reprinted from materials provided by North Carolina State University.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

---

Journal Reference:

1. Jason C. Allaire, Anne Collins McLaughlin, Amanda Trujillo, Laura A. Whitlock, Landon LaPorte, Maribeth Gandy. Successful aging through digital games: Socioemotional differences between older adult gamers and Non-gamers. Computers in Human Behavior, 2013; 29 (4): 1302 DOI: 10.1016/j.chb.2013.01.014

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/strange_science/~3/cksHB7fH8SE/130305131249.htm

julia child Ron Palillo Chad Johnson Twitter Helen Gurley Brown Kathi Goertzen Johnny Pesky spice girls

Connecticut massacre records remain secret

NEW HAVEN, Conn. (AP) ? There is no doubt who is responsible for the Newtown school massacre. The shooter is dead and the prosecutor handling the case has said he does not expect any charges.

Yet authorities are continuing to keep search warrants and police records secret. Media outlets have pressed for the release of more records, which could shed light on a crime that has revived the national debate over gun control and could change the way guns are regulated.

The massacre has led to proposals for universal background checks on gun buyers and bans on assault weapons and high-capacity ammunition magazines. It also prompted reviews of school security and mental health care and led to proposed legislation in Connecticut that would forbid arcades and other establishments from allowing children under 18 to play point-and-shoot video games.

The 20-year-old shooter, Adam Lanza, killed his mother at their home before killing 20 first-graders and six educators at Sandy Hook Elementary School on Dec. 14. He killed himself as police arrived.

Prosecutor Stephen Sedensky III successfully argued in December to keep search warrant affidavits and applications related to Lanza's house and the car he drove to the school sealed for 90 days, saying disclosure would jeopardize an ongoing investigation. He said at the time no arrests were anticipated but had not been ruled out.

News media advocates say the records should be unsealed, arguing the public has a right to see such records, which include what was found in the house and car. They say records may be sealed only when an investigation would be hurt by disclosure.

"There seems to be absolutely no reason that they would need to. It's not going to jeopardize the case in any way," said Linda Petersen, chairwoman of the Freedom of Information Committee of the Society of Professional Journalists.

William Fish, an attorney who has represented the news media in high-profile cases that were sealed in Connecticut, also said the sealing does not appear justified since no prosecution is likely. He conceded, however, that "it's not a surprise to me that a court has in fact sealed the records just because it's so horrible."

Newtown police denied requests by The Associated Press for 911 calls and any police reports involving Lanza or his family. State police also declined to release records, citing the pending investigation.

In an editorial last week, The Hartford Courant said such records should be released sooner, not later, since they might answer the public's questions about the murders and could guide legislators making policy decisions in reaction to the crime.

Richard Hanley, graduate journalism director at Quinnipiac University, said he understood the 90-day sealing while the investigation unfolded but said there should be no extension of that sealing.

"This was a case that had a profound impact on people beyond the immediate area and it will have a profound impact on public policy," Hanley said Monday. "It's imperative that the authorities release the full investigative records, the 911 calls and other documents relative to this slaughter, because the overriding interest is the public's right to know."

Sedensky, the prosecutor, noted that authorities have disclosed details about the weapons used in the shooting: a Bushmaster semi-automatic rifle was used to kill the children and educators and a handgun to kill himself. He said he advised Newtown officials not to disclose the 911 calls.

Danbury Superior Court Judge John F. Blawie on Dec. 27 granted the 90-day seal on search warrant affidavits and applications after concluding that the state's "interest in continuing nondisclosure substantially outweighs any right to public disclosure at this time."

Sedensky said he has not decided yet whether to seek an extension of the sealing. A police report on the probe may not be ready until the summer, he said.

In denying a request by the AP for police reports and 911 calls, the Newtown Police Department said releasing the documents was prohibited by state law "as information to be used in a prospective law enforcement action." AP's request sought all police calls for service to the Lanza house and to Sandy Hook Elementary School, 911 calls and any police reports involving Lanza and his family.

Police Chief Michael Kehoe has said there were only two calls to the Lanza house several years before the shooting. One was in 2006 in which Lanza's mother Nancy reported someone rang the doorbell and ran off and the other was to report a larceny in 2003 that turned out to be in another jurisdiction, Kehoe said.

Source: http://news.yahoo.com/conn-massacre-records-secret-media-seek-access-194010901.html

Univision josh hamilton Susan Rice American Airlines the Who jon bon jovi jon bon jovi

GOP seeks to smooth roughest cuts, avert shutdown

House Speaker John Boehner of Ohio, accompanied by fellow GOP leaders, meets with reporters on Capitol Hill in Washington, Tuesday, March 5, 2013, following a Republican strategy session. From left are, House Majority Whip Kevin McCarthy of Calif., Boehner, House Majority Leader Eric Cantor of Va., and Rep. Steve Daines, R-Mont. (AP Photo/J. Scott Applewhite)

House Speaker John Boehner of Ohio, accompanied by fellow GOP leaders, meets with reporters on Capitol Hill in Washington, Tuesday, March 5, 2013, following a Republican strategy session. From left are, House Majority Whip Kevin McCarthy of Calif., Boehner, House Majority Leader Eric Cantor of Va., and Rep. Steve Daines, R-Mont. (AP Photo/J. Scott Applewhite)

House Speaker John Boehner of Ohio listens during a news conference on Capitol Hill in Washington, Tuesday, March 5, 2013, following a Republican strategy session. (AP Photo/J. Scott Applewhite)

WASHINGTON (AP) ? Republicans controlling the House are moving to take the roughest edges off across-the-board spending cuts that are just starting to take effect.

Even as the military would bear a $43 billion cut over just seven months, the new GOP measure released Monday would give the Pentagon much-needed funding for readiness. It would also ease the pain felt by critical agencies like the FBI and the Border Patrol.

The effort is part of a huge spending measure released Monday that would fund day-to-day federal operations through September ? and head off a potential government shutdown later this month.

"Our goal is to cut spending, not to shut the government down," said House Speaker John Boehner, R-Ohio.

The measure would leave in place automatic cuts of 5 percent to domestic agencies and 7.8 percent to the Pentagon ordered Friday by President Barack Obama after months of battling with Republicans over the budget. But the House Republicans' legislation would award the Defense Department its detailed 2013 budget while other agencies would be frozen in place at 2012 levels.

The unprecedented across-the-board cuts would then be applied to the day-to-day budgets of every federal agency except Veterans Affairs, which is exempt from them.

The GOP funding measure is set to advance through the House on Thursday in hopes of preventing a government shutdown when a six-month spending bill passed last September runs out March 27. The latest measure blends updated 2013 budget measures for the Defense and Veterans Affairs departments ? giving much-sought increases for military operations and maintenance efforts and veterans' health programs ? but puts most the rest of the government on autopilot.

Senate Democrats want to add more detailed budgets for domestic Cabinet agencies but it will take GOP help to do so. The House measure also denies money sought by Obama and his Democratic allies to implement the signature 2010 laws overhauling the health care system and financial regulation.

After accounting for the across-the-board cuts, domestic agencies would face cuts exceeding 5 percent when compared with last year. But Republicans carved out a host of exemptions seeking to protect especially important functions, such as federal prisons and firefighting efforts in the West, as well as new funding for embassy security and modernizing the U.S. nuclear arsenal. The FBI and the Border Patrol would be able to maintain current staffing levels and would not have to furlough employees.

The legislation would provide about $2 billion more than the current level to beef up security at U.S. embassies and diplomatic missions worldwide. Last September, a terrorist attack on the U.S. diplomatic mission in Benghazi, Libya, killed Ambassador Chris Stevens and three other Americans.

A project to repair the iconic Capitol Dome could stay on track and NASA would be protected from the harshest effects of the automatic cuts, known in Washington-speak as a sequester.

The across-the-board cuts would carve $85 billion in spending from the government's $3.6 trillion budget for this year, concentrating the cuts in the approximately $1 trillion allocated to the day-to-day agency operating budgets set by Congress each year. Those so-called discretionary accounts received big boosts in the first two years of Obama's presidency, when Democrats controlled Congress, but have borne the brunt of the cuts approved as Obama and Republicans have grappled over the budget.

Both Democrats and Republicans for months have warned the cuts are draconian and would slow the growth of the economy, costing hundreds of thousands of jobs. The nonpartisan Congressional Budget Office, for instance, says they would slow the economy by 0.6 percent and cost about 750,000 jobs.

Associated Press

Source: http://hosted2.ap.org/apdefault/89ae8247abe8493fae24405546e9a1aa/Article_2013-03-05-Budget%20Battle/id-73327fc616004a068fa37c998e505c8b

nba finals K Michelle roger clemens multiple sclerosis falling skies rodney king Webb Simpson

Luxury Clothing Startup Everlane Crowdfunds Its Canada Launch, Targets More International Growth

It’s becoming very clear that crowdfunding isn’t just for nascent upstart projects anymore. The latest example of this: Everlane, the company that produces and sells luxury clothing and accessories at a discount since it’s online-only and vertically integrated, is raising $100,000 in a crowdsourced campaign to determine whether it will extend its reach into Canada. The effort, which began this morning, has been a big success so far, with some 480 contributors committing more than $32,000 just nine hours into the 17 day campaign. Crowdfunding for data’s sake — not for the money It bears mention that the money raised is not all that’s necessary being to fund the Canadian launch. “We’re not using any of this to fund the operations,” Everlane founder and CEO Michael Preysman said in a phone interview today. “It’s our internal benchmark. We said, ‘If we hit this mark, there are a lot of people in Canada who really want Everlane.’” Looking ahead, Preysman says Everlane is eyeing even more international expansion, with launches in the UK and Australia hopefully on deck by the end of 2013. Today, Everlane currently has more than 500,000 members in the US alone. It’s an interesting example of how crowdfunding can be valuable even for companies that don’t necessarily need the money. Hard data about consumer intent can be hard to come by, and crowdfunding provides concrete feedback about people who are truly interested in something — people who will put money down are clearly pretty serious about wanting a product. Traditionally it’s been used by upstart projects that need the money to take the next step, but this shows that it can be a valuable data collection tool in itself. Making a launch less of a ‘shot in the dark’ It’s a big departure from how small e-commerce companies typically handle international expansion. The status quo way to evaluate which regions to expand to next is counting the inbound requests received via email — an obviously vague way of gauging demand. “Bigger companies can do significantly-sized user studies, but for smaller companies like us, it’s a shot in the dark,” Preysman said. “There have been a number of instances where you see startups enter, say, Europe and it just doesn’t work out.” The risk of something not working out is not one that Everlane was keen to take. “We had a lot of people emailing us asking ‘When

Source: http://feedproxy.google.com/~r/Techcrunch/~3/Rflb3F0Xt8E/

Bronson Pelletier andy reid redskins sugar bowl downton abbey season 3 Buckwild 2013 Calendar

Amazon Takes More Steps Toward Building A Mobile Ad Network With An API In Beta

Amazon is taking the first steps toward building a mobile ad network across its Kindle devices with a new advertising API in beta for developers. If you judge by the earnings of publicly traded mobile advertising companies like Millennial Media, which has had annual losses for the last five years, it’s a tough business with low margins. But Amazon has something that most other competing networks don’t: troves of data on the millions of consumers who buy goods off its site. That could help Amazon understand what kinds of ads actually result in purchases better than Google AdMob, Facebook or any of the independent networks like InMobi or Jumptap. It also means much more seamless calls-to-action embedded in ads that can get users immediately clicking through to buy products. Amazon is kicking off the network with advertisers like Duracell Powermat and Nature’s Bounty. For now, Amazon’s mobile ads API will only work with U.S. users and apps and games on the Kindle Fire, Kindle Fire HD and other Android phones and tablets. If a developer does use the API, they have to make sure that their apps are also available for download on Amazon’s app store. The network has two types of ads: static clickthrough banners and then banners that can expand to include rich media like video. They have calls to action that usually involve opening an in-app or native browser. There’s room for basic geo-targeting with using latitude and longitude coordinates if a user has chosen to share them with an app. Publishers can also blacklist certain advertisers they don’t want or think are appropriate for their users. So far, Amazon has shied away from making a big purchase of an independent mobile ad network. That’s unlike Apple or Google, which bought Quattro and AdMob respectively back in 2010. While the AdMob deal is generally considered to have worked out well for Google, Apple’s effort to turn Quattro into a premium mobile ad network like iAd sputtered as brand advertisers balked at the upfront spending commitments the company initially asked for. It seems that Amazon is taking a more conservative approach with more traditional ad formats and advertisers that already sell products on its site. The ads API comes on top of a host of other mobile app infrastructure products Amazon has built over the last year including a mobile gaming network, GameCircle, a virtual currency and in-app

Source: http://feedproxy.google.com/~r/Techcrunch/~3/IVmoFMuqW98/

monta ellis wiz khalifa taylor allderdice mixtape reggie wayne taylor allderdice vincent jackson vicki gunvalson pierre garcon

GOP's anti-tax focus trips Dems in budget battle

House Speaker John Boehner of Ohio smiles during a news conference on Capitol Hill in Washington, Tuesday, March 5, 2013, following a Republican strategy session. Congressional Republicans? unyielding stand against income tax increases has caught President Barack Obama and his allies off guard. The result is a spending-cuts-only approach to deficit reduction that Democrats wanted to avoid. The events have dimmed hopes for broader efforts to start taming costly ?entitlement? programs such as Medicare and Social Security. (AP Photo/J. Scott Applewhite)

House Speaker John Boehner of Ohio smiles during a news conference on Capitol Hill in Washington, Tuesday, March 5, 2013, following a Republican strategy session. Congressional Republicans? unyielding stand against income tax increases has caught President Barack Obama and his allies off guard. The result is a spending-cuts-only approach to deficit reduction that Democrats wanted to avoid. The events have dimmed hopes for broader efforts to start taming costly ?entitlement? programs such as Medicare and Social Security. (AP Photo/J. Scott Applewhite)

House Speaker John Boehner of Ohio, accompanied by fellow GOP leaders, meets with reporters on Capitol Hill in Washington, Tuesday, March 5, 2013, following a Republican strategy session. From left are, House Majority Whip Kevin McCarthy of Calif., Boehner, House Majority Leader Eric Cantor of Va., and Rep. Steve Daines, R-Mont. (AP Photo/J. Scott Applewhite)

WASHINGTON (AP) ? Congressional Republicans' unyielding stand against income tax increases has caught President Barack Obama and his allies off guard, resulting in the spending-cuts-only approach to deficit reduction that Democrats most wanted to avoid.

It also has dimmed hopes for broader efforts this year to start taming the costly and fast-growing "entitlement" programs of Medicare and Social Security.

The result is a new round of deficit reduction that tilts more toward Republicans' wishes than many people would have expected after Obama won re-election with a campaign that called for higher taxes on the rich.

Democrats thought House Republicans would accept some new revenues last month to minimize military cuts and to pressure liberals to confront entitlement spending. Instead, Republicans seem more determined than ever to block tax increases on high incomes, whatever the political risk.

It's now the overriding priority for GOP lawmakers ? even if they hold a different view of payroll taxes on wage earners. With relatively little debate, Republicans and Democrats this year raised the payroll tax rate, which funds Social Security, after granting a two-year reduction.

In all, two years of budget debates have yielded laws to reduce deficits by nearly $4 trillion over 10 years, a point of pride for Republicans. About $620 billion of that will come from tax hikes made inevitable by the "fiscal cliff" legislation, resolved on Jan. 1. The rest will come from spending cuts and savings on interest.

The ratio disappoints liberals. They recall that Congress' top Republican suggested $800 billion in new revenue, and Obama proposed $1.2 trillion or more, in "grand bargain" talks that started in 2011 but never reached fruition.

"Somehow we ended up with $600 billion," and with no provisions to rein in entitlements, says Jim Kessler of the Democratic think tank Third Way. "It was an enormous missed opportunity."

For House Republicans, the no-income-tax-increase stand is more doctrine than strategy. Whether lucky or strategic, however, they feel they outfoxed Obama on deficit-reduction policies this time.

When a new "fiscal cliff" law was about to raise income tax rates on nearly all U.S earners in January, GOP leaders accepted Obama's offer to limit the increase to incomes above $450,000. It was a concession by the president, who had campaigned for a somewhat broader tax hike.

Republicans never reciprocated, however. That cleared the way last week for across-the-board "sequester" spending cuts, once considered too damaging to enact. The deal contains none of the new revenues that Democrats had hoped would follow their compromise on the fiscal cliff.

"It a result of botched negotiations on the fiscal cliff," Kessler said. "There is now no forcing mechanism for Democrats to come to the table on entitlements and for Republicans to come to the table on revenue."

The government is cutting into discretionary spending rather than investing in education, infrastructure and other future-oriented priorities, Kessler said.

Republicans say income tax rate hikes inhibit hiring. Democrats note that the federal tax burden, as a portion of the economy, is the lowest it has been since 1950. Also, nonpartisan studies show that the Bush-era tax cuts contributed heavily to the deficit.

Some Republicans say they outflanked Obama last week simply by adamantly opposing higher income taxes. It's a priority they reinforced at a January gathering in Williamsburg, Va.

"The strategy we've been embarked on since Williamsburg ? which is no budget, no pay; lock in the sequester savings; get the CR done ? so far, that's working," said Rep. Jim Jordan of Ohio, a prominent House conservative. He was alluding to House efforts to force senators to pass a budget (or forgo their pay), and to open the way for a "continuing resolution" to keep the government operating beyond March 27, with no increase in revenues.

Kevin Smith, a spokesman for House Speaker John Boehner, said: "We're exactly where we set out to be a few weeks ago."

The GOP strategy carries risks. Polls show Americans are more inclined to blame Republicans than Democrats if the budget reductions damage the economy or significantly inconvenience people's day-to-day lives.

Louisiana Gov. Bobby Jindal and other non-Washington Republicans say congressional Republicans are too obsessed with austerity and budget numbers, risking a public backlash if programs are cut too deeply or unwisely.

A CBS News poll finds large majorities of Americans saying they want both parties to compromise rather than hold fast to their positions. Self-identified Democrats, however, embrace compromise more than Republicans do.

GOP strategist Mike McKenna thinks House Republicans took a smart, calculated risk by letting the sequester cuts take place. "Most people don't interact with the federal government a lot," he said.

While most Americans support a mix of budget cuts and tax increases to reduce the deficit, McKenna said, they realize the payroll tax rose in January, along with the tax on incomes above $450,000.

With the deficit-spending battles apparently cooling for a while, Congress can focus more heavily on immigration, gun control and other issues.

Congressional Republicans say they're confident that few if any changes will be made to gun laws. As for immigration, most are taking a wait-and-see approach.

Many conservative activists oppose "amnesty" for illegal immigrants. But Republican strategists say the party will struggle to win presidential elections unless it improves its relationship with Hispanic voters, many of whom see immigration as important symbolically and substantively.

House Republicans "are so caught up in the sequester thing, they're not thinking four weeks down the road," McKenna said.

For now, they seem content without a grand strategy, and some Democrats are wincing.

Democratic consultant Jim Manley, who confers often with Obama aides, said those aides feel the president used his fiscal cliff leverage to his advantage on Jan. 1. But on the sequester, they concede that Republicans returned the favor and had the upper hand, Manley said.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-03-05-Budget%20Battle-Republican%20Strategy/id-ff3821e097ce4e59a1920aa8e83b91e4

nfl mock draft project m colts colts big ten tournament 2012 dennis quaid bruce weber fired

How many frogs does it take to make a handbag? Tokyo museum has the answer

Tucked away in Tokyo is a little trafficked museum that houses bags from the world over. It is an unexpected reminder of how much more than a bag a piece of luggage can be.

By Peter Ford,?Staff Writer / March 3, 2013

The World Bags and Luggage Museum is home to the personal collection of the owner of Japan's Ace luggage company (the world's first producer of nylons bags). It houses more than 400 examples of handbags, travel bags, and trunks made from everything from Zebra to frog.

Peter Ford/The Christian Science Monitor

Enlarge

Hidenori Hirosaki acknowledges that the museum of which he is the director is ?unusual.?

Skip to next paragraph Peter Ford

Beijing Bureau Chief

Peter Ford is The Christian Science Monitor?s Beijing Bureau Chief. He covers news and features throughout China and also makes reporting trips to Japan and the Korean peninsula.

Recent posts

' + google_ads[0].line2 + '
' + google_ads[0].line3 + '

'; } else if (google_ads.length > 1) { ad_unit += ''; } } document.getElementById("ad_unit").innerHTML += ad_unit; google_adnum += google_ads.length; return; } var google_adnum = 0; google_ad_client = "pub-6743622525202572"; google_ad_output = 'js'; google_max_num_ads = '1'; google_feedback = "on"; google_ad_type = "text"; google_adtest = "on"; google_image_size = '230x105'; google_skip = '0'; // -->

Subscribe Today to the Monitor

Click Here for your FREE 30 DAYS of
The Christian Science Monitor
Weekly Digital Edition

He is proud, he says, that ?it is unique. There is no other museum with this concept in the world.?

Mr. Hirosaki is the director and driving force behind the World Bags and Luggage Museum, a shrine that imbues the humble suitcase with a sacred quality.

On display, picked out like jewels by artful lighting, are satchels and steamer trunks, backpacks and portmanteaus, clutch bags and briefcases from around the world and down the ages.

The collection began with Ryusaku Shinkawa, the founder of ACE, a Japanese luggage manufacturer, who gathered many of the pieces that are now on show for the small and little-visited museum. The late Mr. Shinkawa, described in the museum brochure as ?pursuing bag as divine vocation,? was clearly passionate about his business.

Hirosaki has inherited his enthusiasm, and his taste is eclectic. As a man who has worked for ACE and lived with leather all his adult life (?the first thing I notice about a man is his shoes,? he says), he cannot disguise his preference for perfectly tanned cowhide and the workmanship that went into classic Italian luggage in the 1960s.

But he is just as keen to show off a navy blue Panam flight bag, made in 1960, which Hirosaki explains in the descriptive panel alongside the bag, was ?a longing symbol of overseas travel for us Japanese.? Japanese were not allowed to go abroad, except on business or to study, until 1964, he recalls.

The museum, housed on the seventh floor of the ACE corporation?s headquarters, owns about 600 pieces (and the collection is growing: Hirosaki bought the Panam bag last year on eBay for $150) but only half of them are on display. Even so, they encompass an extraordinary variety of things for putting things in.

Zebra, water buffalo, hippopotamus, oh my

There is a pair of zebra skin travel bags; an elephant hide suitcase that once belonged to a Kuwaiti emir; one attach? case made from rich yellow water buffalo hide, another of hippopotamus leather, and a third from deeply crevassed sharkskin.

There is a trunk covered with the black skins of 12 saltwater crocodiles, gleaming like patent leather; there is an elk-skin shoulder bag from Finland, a barrel-topped Saratoga trunk from the United States, and an elegant clutch made in Thailand from a patchwork of pale green and delicate yellow rectangles.

?A considerable number of frogs are needed to make a single bag,? a sign explains.

And did you ever wonder why a Saratoga trunk had that distinctive barrel-shaped lid? In the days of carriage and train travel when cases were piled on top of each other, a Saratoga trunk could only go on top of the pile, thus running less risk of damage.

The museum embraces the modern and the practical with as much ardor as it reserves for the exotic and luxurious. Hirosaki waxes lyrical in his description of the first Samsonite suitcase that ACE made under license, (the classic Silhouette, whose subtle wedge shape has defined the brand for half a century), describing it as ?a flower on a lofty height.?

In another glass display case nearby is an even more prosaic looking item ? a grey aluminum box with an orange Bakelite handle, secured by a couple of hasps.

This, it turns out, is the toolbox that Richard Halliburton designed for himself in 1938. The American engineer, scion of the oil-services giant bearing his name, ?through his bitter experience in the Middle East that inside of a bag get covered in sand, decided to invent a case of his own satisfactory,? Hirosaki?s sign explains in somewhat fractured English.

A very similar, though somewhat larger, box was used by the Apollo 11 crew to store moon-rocks, says a sign. ?The spec. was nothing special, with slight interior modification, which proved the case valid in universe.?

Valid throughout the universe. What greater praise could be bestowed on a travel accessory?

Just before the exit, the last display area in the museum shows off ACE?s current output ? fairly standard pieces of lightweight, robust luggage in bright colors equipped with the casters and pullout handles familiar from airports the world over.

Hirosaki is proud that ACE is Japan?s only remaining luggage manufacturer, but he cannot hide his nostalgia for the glory days of luxury travel and the exquisitely crafted baggage that went with it.

?Today people put too much stress on rationality, functionality, and efficiency,? he sighs, admiring a strapped suitcase made from natural leather by the Italian company Franzi (where Guccio Gucci got his start) half a century ago.

The sign beside the case is simple and eloquent. ?The same cannot be manufactured under the present circumstances of attaching too much emphasis to productivity,? it says. The World Bags and Luggage Museum is an unexpected reminder of how much more than a bag a bag can be.

(The museum can be found in the Asakusa district of Tokyo at 1-8-10 Komagata, Taito Ku, Tokyo. Phone 03-3847-5680)

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/rAL65GKdQwY/How-many-frogs-does-it-take-to-make-a-handbag-Tokyo-museum-has-the-answer

Superbowl Kickoff Time 2013 What Time Is The Super Bowl 2013 Super Bowl 2013 Time BlackBerry 10 superbowl jackie robinson Ron Jeremy

Mouse Study Sheds Light On Why Some Cancer Vaccines Fail

A simple switch of ingredients made a big difference in how mice responded to experimental cancer vaccines.

Andrei Tchernov/iStockphoto.com

A simple switch of ingredients made a big difference in how mice responded to experimental cancer vaccines.

Andrei Tchernov/iStockphoto.com

In the quest for better cancer medicines, vaccines that treat rather than prevent disease are getting lots of attention.

More than 90 clinical trials have tested therapeutic vaccines in cancer patients, but the results have been a mixed bag.

A recent study in mice suggests that changing a traditional ingredient in the vaccines could make a big difference.

A typical therapeutic vaccine against cancer contains a cancer-specific peptide, or protein fragment, that is injected under a patient's skin. The peptide serves as a red flag for the immune system. If all goes well, the patient's immune system recognizes the peptide as something to be attacked and boosts the population of cancer-fighting T-cells in the bloodstream.

For such vaccines to work against the cancers, though, these cells have to find their way to tumors. This migration might not be happening as expected in traditional human cancer vaccines, says Willem Overwijk, an author of the study in the latest Nature Medicine and an assistant professor at MD Anderson Cancer Center in Houston.

Cancer vaccines typically include a substance called IFA, short for "incomplete Freund's adjuvant." Adjuvants are chemicals added to vaccines to stimulate an immune response.

"IFA is a mineral oil that is not biodegradable by the body," says Overwijk. This was thought to be helpful in cancer vaccines because the longer the vaccine sticks around in the body, the greater the immune response and the more T-cells that can be produced, Overwijk says.

But when mice were injected with an IFA vaccine against melanoma, the study reports that most of the T-cells in the bloodstream went to the site of the vaccine injection ? not the tumor.

"The body doesn't know how to deal with the mineral oil [in IFA], and the body cannot get rid of that big blob of vaccine ... that sits under the skin. The T-cells go back and try to kill the oil, but they can't," he says.

When the oily IFA was replaced with water or saline ? substances easily processed by mice and men ? the T-cells migrated to the tumors and began to destroy them.

If these results hold up in humans, they could lead to a shift in the approach to making therapeutic cancer vaccines because most clinical trials now are testing vaccines that use peptides and IFA. "This finding applies to all of those ? it's not limited to a certain cancer type," Overwijk says.

The results of this study confirm the findings of others in the field, and could be an important addition to cancer vaccine research, says Dr. Jeffery Weber, a tumor immunologist at the Moffitt Cancer Center in Tampa, Florida, who wasn't associated with the study.

"Though, one word of caution is that obviously the skin and the subcutaneous tissue of a mouse is a lot different than in a human, so it's a little hard to extrapolate. But within the reasonable limits I have some confidence," Weber told Shots.

Overwijk and collaborators at the University of Virginia expect to start a human clinical trial using saline or water-based cancer vaccines sometime this year. But, he says, these non-IFA vaccines have problems, too.

"While it is better than the IFA, we think water may actually be a little too ephemeral. Too short, and you don't get the activation of the immune system." Overwijk says. Another barrier is the difficulty in tracking human T-cells via biopsy ? a process that wasn't necessary in mice, where the cells could be fluorescently labeled.

Though there are plenty of unresolved issue in cancer vaccine research, Overwijk says that these results could be important for improving future clinical trials. It's "an eye-opener," he says, a kind of "'Aha!' moment after years of using these same vaccines."

Source: http://www.npr.org/blogs/health/2013/03/04/173412469/mouse-study-sheds-light-on-why-some-cancer-vaccines-fail?ft=1&f=1007

Ada Lovelace 12/12/12 manny pacquiao Chopper Live jerry brown michael buble michael buble